20(S)-Ginsenoside Rh2 displays efficacy against T-cell acute lymphoblastic leukemia through the PI3K/Akt/mTOR signal pathway

BACKGROUND: T-cell acute lymphoblastic leukemia (T-ALL) is a kind of aggressive hematological cancer, and the PI3K/Akt/mTOR signaling pathway is activated in most patients with T-ALL and responsible for poor prognosis. 20(S)-Ginsenoside Rh2 (20(S)-GRh2) is a major active compound extracted from gins...

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Detalles Bibliográficos
Autores principales: Xia, Ting, Zhang, Jin, Zhou, Chuanxin, Li, Yu, Duan, Wenhui, Zhang, Bo, Wang, Min, Fang, Jianpei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Pharmacology & Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471214/
https://www.ncbi.nlm.nih.gov/pubmed/32913402
http://dx.doi.org/10.1016/j.jgr.2019.07.003

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