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Untargeted lipidomics reveals progression of early Alzheimer’s disease in APP/PS1 transgenic mice

Alzheimer’s Disease (AD) is closely connected to aberrant lipid metabolism. However, how early AD-like pathology synchronously influences brain and plasma lipidome in AD mice remains unclear. The study of dynamic change of lipidome in early-stage AD mice could be of great interest for the discovery...

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Detalles Bibliográficos
Autores principales: Zhang, Xueju, Liu, Weiwei, Zan, Jie, Wu, Chuanbin, Tan, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471266/
https://www.ncbi.nlm.nih.gov/pubmed/32884056
http://dx.doi.org/10.1038/s41598-020-71510-z