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Ontological approach to the knowledge systematization of a toxic process and toxic course representation framework for early drug risk management

Various types of drug toxicity can halt the development of a drug. Because drugs are xenobiotics, they inherently have the potential to cause injury. Clarifying the mechanisms of toxicity to evaluate and manage drug safety during drug development is extremely important. However, toxicity mechanisms,...

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Detalles Bibliográficos
Autores principales: Yamagata, Yuki, Yamada, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471325/
https://www.ncbi.nlm.nih.gov/pubmed/32883995
http://dx.doi.org/10.1038/s41598-020-71370-7