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Ontological approach to the knowledge systematization of a toxic process and toxic course representation framework for early drug risk management
Various types of drug toxicity can halt the development of a drug. Because drugs are xenobiotics, they inherently have the potential to cause injury. Clarifying the mechanisms of toxicity to evaluate and manage drug safety during drug development is extremely important. However, toxicity mechanisms,...
Autores principales: | Yamagata, Yuki, Yamada, Hiroshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471325/ https://www.ncbi.nlm.nih.gov/pubmed/32883995 http://dx.doi.org/10.1038/s41598-020-71370-7 |
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