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Cycloastragenol upregulates SIRT1 expression, attenuates apoptosis and suppresses neuroinflammation after brain ischemia

Cycloastragenol (CAG) is the active form of astragaloside IV isolated from Astragalus Radix, which displays multiple pharmacological effects. Silent information regulator 1 (SIRT1), a class III histone deacetylase, has been shown to play an important role in neuroprotection against cerebral ischemia...

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Detalles Bibliográficos
Autores principales:	Li, Man, Li, Shi-chun, Dou, Bao-kai, Zou, Ying-xiang, Han, Hao-zhen, Liu, Dong-xiang, Ke, Zun-ji, Wang, Zhi-fei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Singapore 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471431/ https://www.ncbi.nlm.nih.gov/pubmed/32203080 http://dx.doi.org/10.1038/s41401-020-0386-6

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