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Asiatic acid prevents renal fibrosis in UUO rats via promoting the production of 15d-PGJ2, an endogenous ligand of PPAR-γ

Renal fibrosis is an inevitable outcome of all kinds of progressive chronic kidney disease (CKD). Recently, asiatic acid (AA), a triterpenoid compound from Chinese medicine Centella asiatica, has been found to attenuate renal fibrosis. In the current study, we explored the mechanisms underlying anti...

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Detalles Bibliográficos
Autores principales:	Zhang, Zhi-hao, He, Jun-qiu, Zhao, Ying-yong, Chen, Hua-chao, Tan, Ning-hua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Singapore 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471452/ https://www.ncbi.nlm.nih.gov/pubmed/31705123 http://dx.doi.org/10.1038/s41401-019-0319-4

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