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Zinc protects against cadmium-induced toxicity in neonatal murine engineered cardiac tissues via metallothionein-dependent and independent mechanisms
Cadmium (Cd) is a nonessential heavy metal and a prevalent environmental toxin that has been shown to induce significant cardiomyocyte apoptosis in neonatal murine engineered cardiac tissues (ECTs). In contrast, zinc (Zn) is a potent metallothionein (MT) inducer, which plays an important role in pro...
Autores principales: | Yu, Hai-tao, Zhen, Juan, Xu, Jian-xiang, Cai, Lu, Leng, Ji-yan, Ji, Hong-lei, Keller, Bradley B |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Singapore
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471469/ https://www.ncbi.nlm.nih.gov/pubmed/31768045 http://dx.doi.org/10.1038/s41401-019-0320-y |
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