Cargando…

Application of Phage-Displayed Peptides in Tumor Imaging Diagnosis and Targeting Therapy

Phage display is an effective and powerful technique that provides a route to discovery unique peptides targeting to tumor cells. Specifically binding peptides are considered as the valuable target directing molecule fragments with potential efficiency to improve the current tumor clinic, and offer...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Chunyan, Li, Jia, Xu, Ying, Zhan, Ying, Li, Yu, Song, Tingting, Zheng, Jiao, Yang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471523/
https://www.ncbi.nlm.nih.gov/pubmed/32901205
http://dx.doi.org/10.1007/s10989-020-10108-5
_version_ 1783578785749139456
author Li, Chunyan
Li, Jia
Xu, Ying
Zhan, Ying
Li, Yu
Song, Tingting
Zheng, Jiao
Yang, Hong
author_facet Li, Chunyan
Li, Jia
Xu, Ying
Zhan, Ying
Li, Yu
Song, Tingting
Zheng, Jiao
Yang, Hong
author_sort Li, Chunyan
collection PubMed
description Phage display is an effective and powerful technique that provides a route to discovery unique peptides targeting to tumor cells. Specifically binding peptides are considered as the valuable target directing molecule fragments with potential efficiency to improve the current tumor clinic, and offer new approaches for tumor prevention, diagnosis and treatment. We focus on the recent advances in the isolation of tumor-targeting peptides by biopanning methods, with particular emphasis on molecular imaging, and pharmaceutical targeting therapy.
format Online
Article
Text
id pubmed-7471523
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Springer Netherlands
record_format MEDLINE/PubMed
spelling pubmed-74715232020-09-04 Application of Phage-Displayed Peptides in Tumor Imaging Diagnosis and Targeting Therapy Li, Chunyan Li, Jia Xu, Ying Zhan, Ying Li, Yu Song, Tingting Zheng, Jiao Yang, Hong Int J Pept Res Ther Article Phage display is an effective and powerful technique that provides a route to discovery unique peptides targeting to tumor cells. Specifically binding peptides are considered as the valuable target directing molecule fragments with potential efficiency to improve the current tumor clinic, and offer new approaches for tumor prevention, diagnosis and treatment. We focus on the recent advances in the isolation of tumor-targeting peptides by biopanning methods, with particular emphasis on molecular imaging, and pharmaceutical targeting therapy. Springer Netherlands 2020-09-03 2021 /pmc/articles/PMC7471523/ /pubmed/32901205 http://dx.doi.org/10.1007/s10989-020-10108-5 Text en © Springer Nature B.V. 2020 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Article
Li, Chunyan
Li, Jia
Xu, Ying
Zhan, Ying
Li, Yu
Song, Tingting
Zheng, Jiao
Yang, Hong
Application of Phage-Displayed Peptides in Tumor Imaging Diagnosis and Targeting Therapy
title Application of Phage-Displayed Peptides in Tumor Imaging Diagnosis and Targeting Therapy
title_full Application of Phage-Displayed Peptides in Tumor Imaging Diagnosis and Targeting Therapy
title_fullStr Application of Phage-Displayed Peptides in Tumor Imaging Diagnosis and Targeting Therapy
title_full_unstemmed Application of Phage-Displayed Peptides in Tumor Imaging Diagnosis and Targeting Therapy
title_short Application of Phage-Displayed Peptides in Tumor Imaging Diagnosis and Targeting Therapy
title_sort application of phage-displayed peptides in tumor imaging diagnosis and targeting therapy
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471523/
https://www.ncbi.nlm.nih.gov/pubmed/32901205
http://dx.doi.org/10.1007/s10989-020-10108-5
work_keys_str_mv AT lichunyan applicationofphagedisplayedpeptidesintumorimagingdiagnosisandtargetingtherapy
AT lijia applicationofphagedisplayedpeptidesintumorimagingdiagnosisandtargetingtherapy
AT xuying applicationofphagedisplayedpeptidesintumorimagingdiagnosisandtargetingtherapy
AT zhanying applicationofphagedisplayedpeptidesintumorimagingdiagnosisandtargetingtherapy
AT liyu applicationofphagedisplayedpeptidesintumorimagingdiagnosisandtargetingtherapy
AT songtingting applicationofphagedisplayedpeptidesintumorimagingdiagnosisandtargetingtherapy
AT zhengjiao applicationofphagedisplayedpeptidesintumorimagingdiagnosisandtargetingtherapy
AT yanghong applicationofphagedisplayedpeptidesintumorimagingdiagnosisandtargetingtherapy