Cargando…
Emodin alleviates gemcitabine resistance in pancreatic cancer by inhibiting MDR1/P-glycoprotein and MRPs expression
Gemcitabine is a gold standard chemotherapeutic agent for pancreatic cancer. However, gemcitabine has limited effectiveness due to the short-term development of chemoresistance. Emodin, a natural anthraquinone derivative isolated from the roots of rheumatic palm leaves prevents immunosuppression and...
Autores principales: | Guo, Hongchun, Liu, Feng, Yang, Shuguang, Xue, Tao |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471752/ https://www.ncbi.nlm.nih.gov/pubmed/32934734 http://dx.doi.org/10.3892/ol.2020.12030 |
Ejemplares similares
-
Emodin reverses leukemia multidrug resistance by competitive inhibition and downregulation of P-glycoprotein
por: Min, Hongping, et al.
Publicado: (2017) -
Emodin reverses gemcitabine resistance in pancreatic cancer cells via the mitochondrial apoptosis pathway in vitro
por: LIU, DIAN-LEI, et al.
Publicado: (2011) -
Emodin reverses resistance to gemcitabine in pancreatic cancer by suppressing stemness through regulation of the epithelial‑mesenchymal transition
por: Wei, Weitian, et al.
Publicado: (2022) -
Emodin Reverses Gemcitabine Resistance of Pancreatic Cancer Cell Lines Through Inhibition of IKKβ/NF-κB Signaling Pathway
por: Tong, Hongfei, et al.
Publicado: (2020) -
Plasmodium falciparum Multidrug Resistance Proteins (pfMRPs)
por: Gil, José Pedro, et al.
Publicado: (2021)