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Characteristics and clinical trial results of agonistic anti-CD40 antibodies in the treatment of malignancies

Cluster of differentiation 40 (CD40) mediates many immune activities. Preclinical studies have shown that activation of CD40 can evoke massive antineoplastic effects in several tumour models in vivo, providing a rationale for using CD40 agonists in cancer immunotherapy. To date, several potential ag...

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Detalles Bibliográficos
Autores principales: Li, Da-Ke, Wang, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471753/
https://www.ncbi.nlm.nih.gov/pubmed/32934743
http://dx.doi.org/10.3892/ol.2020.12037

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