Emergence of plasmid-borne bla (oxa-181) gene in Ochrobactrum intermedium: first report from India

Wastewater has become a potential habitat for multi-drug-resistant bacteria. The present study aims to screen for the presence of carbapenem-resistant bacteria in sewage water samples collected from hospital and non-hospital sources. From a total of 19 sewage water samples collected, 100 carbapenem-...

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Autores principales: Shanthini, Thamaraiselvan, Manohar, Prasanth, Samna, Sagadevan, Srividya, Rajendran, Bozdogan, Bulent, Rameshpathy, Manian, Ramesh, Nachimuthu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2019
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471779/
https://www.ncbi.nlm.nih.gov/pubmed/32974517
http://dx.doi.org/10.1099/acmi.0.000024
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author Shanthini, Thamaraiselvan
Manohar, Prasanth
Samna, Sagadevan
Srividya, Rajendran
Bozdogan, Bulent
Rameshpathy, Manian
Ramesh, Nachimuthu
author_facet Shanthini, Thamaraiselvan
Manohar, Prasanth
Samna, Sagadevan
Srividya, Rajendran
Bozdogan, Bulent
Rameshpathy, Manian
Ramesh, Nachimuthu
author_sort Shanthini, Thamaraiselvan
collection PubMed
description Wastewater has become a potential habitat for multi-drug-resistant bacteria. The present study aims to screen for the presence of carbapenem-resistant bacteria in sewage water samples collected from hospital and non-hospital sources. From a total of 19 sewage water samples collected, 100 carbapenem-resistant non-lactose-fermenting Gram-negative bacteria (CR-NF-GNB) were isolated using MacConkey agar cultured with 8 mg l(−1) of meropenem. On screening for beta-lactamase resistance genes (bla (NDM), bla (OXA-48-like), bla (IMP), bla (VIM) and bla (KPC)), one isolate, Ochrobactrum intermedium , was found to carry the plasmid-borne bla (OXA-48-like) gene. To the best of our knowledge, we provide the first report of the rare and emerging opportunistic pathogen Ochrobactrum intermedium encoding the OXA-181 gene in its plasmid.
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spelling pubmed-74717792020-09-23 Emergence of plasmid-borne bla (oxa-181) gene in Ochrobactrum intermedium: first report from India Shanthini, Thamaraiselvan Manohar, Prasanth Samna, Sagadevan Srividya, Rajendran Bozdogan, Bulent Rameshpathy, Manian Ramesh, Nachimuthu Access Microbiol Short Communication Wastewater has become a potential habitat for multi-drug-resistant bacteria. The present study aims to screen for the presence of carbapenem-resistant bacteria in sewage water samples collected from hospital and non-hospital sources. From a total of 19 sewage water samples collected, 100 carbapenem-resistant non-lactose-fermenting Gram-negative bacteria (CR-NF-GNB) were isolated using MacConkey agar cultured with 8 mg l(−1) of meropenem. On screening for beta-lactamase resistance genes (bla (NDM), bla (OXA-48-like), bla (IMP), bla (VIM) and bla (KPC)), one isolate, Ochrobactrum intermedium , was found to carry the plasmid-borne bla (OXA-48-like) gene. To the best of our knowledge, we provide the first report of the rare and emerging opportunistic pathogen Ochrobactrum intermedium encoding the OXA-181 gene in its plasmid. Microbiology Society 2019-05-15 /pmc/articles/PMC7471779/ /pubmed/32974517 http://dx.doi.org/10.1099/acmi.0.000024 Text en © 2019 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License.
spellingShingle Short Communication
Shanthini, Thamaraiselvan
Manohar, Prasanth
Samna, Sagadevan
Srividya, Rajendran
Bozdogan, Bulent
Rameshpathy, Manian
Ramesh, Nachimuthu
Emergence of plasmid-borne bla (oxa-181) gene in Ochrobactrum intermedium: first report from India
title Emergence of plasmid-borne bla (oxa-181) gene in Ochrobactrum intermedium: first report from India
title_full Emergence of plasmid-borne bla (oxa-181) gene in Ochrobactrum intermedium: first report from India
title_fullStr Emergence of plasmid-borne bla (oxa-181) gene in Ochrobactrum intermedium: first report from India
title_full_unstemmed Emergence of plasmid-borne bla (oxa-181) gene in Ochrobactrum intermedium: first report from India
title_short Emergence of plasmid-borne bla (oxa-181) gene in Ochrobactrum intermedium: first report from India
title_sort emergence of plasmid-borne bla (oxa-181) gene in ochrobactrum intermedium: first report from india
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471779/
https://www.ncbi.nlm.nih.gov/pubmed/32974517
http://dx.doi.org/10.1099/acmi.0.000024
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