Fatal Mucormycosis and Aspergillosis in an Atypical Host: What Do We Know about Mixed Invasive Mold Infections?

Mixed invasive mold infections (MIMIs) are considered rare. We present a case of fatal aspergillosis and mucormycosis in an elderly host with history of chronic lymphocytic leukemia (CLL) and potential mold exposures. Notably, he had no classic risk factors for IMI other than high-dose corticosteroi...

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Autores principales: Tsikala-Vafea, Maria, Cao, Weibiao, Olszewski, Adam J., Donahue, John E., Farmakiotis, Dimitrios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471810/
https://www.ncbi.nlm.nih.gov/pubmed/32908735
http://dx.doi.org/10.1155/2020/8812528
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author Tsikala-Vafea, Maria
Cao, Weibiao
Olszewski, Adam J.
Donahue, John E.
Farmakiotis, Dimitrios
author_facet Tsikala-Vafea, Maria
Cao, Weibiao
Olszewski, Adam J.
Donahue, John E.
Farmakiotis, Dimitrios
author_sort Tsikala-Vafea, Maria
collection PubMed
description Mixed invasive mold infections (MIMIs) are considered rare. We present a case of fatal aspergillosis and mucormycosis in an elderly host with history of chronic lymphocytic leukemia (CLL) and potential mold exposures. Notably, he had no classic risk factors for IMI other than high-dose corticosteroids, which may be an important risk factor for (M)IMI, based on the current and previous reports. There is an urgent need for studies on the “net state of immunosuppression,” environmental exposure as risk factors for (M)IMIs, and noninvasive fungal diagnostics.
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spelling pubmed-74718102020-09-08 Fatal Mucormycosis and Aspergillosis in an Atypical Host: What Do We Know about Mixed Invasive Mold Infections? Tsikala-Vafea, Maria Cao, Weibiao Olszewski, Adam J. Donahue, John E. Farmakiotis, Dimitrios Case Rep Infect Dis Case Report Mixed invasive mold infections (MIMIs) are considered rare. We present a case of fatal aspergillosis and mucormycosis in an elderly host with history of chronic lymphocytic leukemia (CLL) and potential mold exposures. Notably, he had no classic risk factors for IMI other than high-dose corticosteroids, which may be an important risk factor for (M)IMI, based on the current and previous reports. There is an urgent need for studies on the “net state of immunosuppression,” environmental exposure as risk factors for (M)IMIs, and noninvasive fungal diagnostics. Hindawi 2020-08-25 /pmc/articles/PMC7471810/ /pubmed/32908735 http://dx.doi.org/10.1155/2020/8812528 Text en Copyright © 2020 Maria Tsikala-Vafea et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Tsikala-Vafea, Maria
Cao, Weibiao
Olszewski, Adam J.
Donahue, John E.
Farmakiotis, Dimitrios
Fatal Mucormycosis and Aspergillosis in an Atypical Host: What Do We Know about Mixed Invasive Mold Infections?
title Fatal Mucormycosis and Aspergillosis in an Atypical Host: What Do We Know about Mixed Invasive Mold Infections?
title_full Fatal Mucormycosis and Aspergillosis in an Atypical Host: What Do We Know about Mixed Invasive Mold Infections?
title_fullStr Fatal Mucormycosis and Aspergillosis in an Atypical Host: What Do We Know about Mixed Invasive Mold Infections?
title_full_unstemmed Fatal Mucormycosis and Aspergillosis in an Atypical Host: What Do We Know about Mixed Invasive Mold Infections?
title_short Fatal Mucormycosis and Aspergillosis in an Atypical Host: What Do We Know about Mixed Invasive Mold Infections?
title_sort fatal mucormycosis and aspergillosis in an atypical host: what do we know about mixed invasive mold infections?
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471810/
https://www.ncbi.nlm.nih.gov/pubmed/32908735
http://dx.doi.org/10.1155/2020/8812528
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