Targeting FcRn for immunomodulation: Benefits, risks, and practical considerations

The neonatal fragment crystallizable (Fc) receptor (FcRn) functions as a recycling mechanism to prevent degradation and extend the half-life of IgG and albumin in the circulation. Several FcRn inhibitors selectively targeting IgG recycling are now moving rapidly toward clinical practice in neurology...

Descripción completa

Detalles Bibliográficos
Autores principales: Peter, Hans-Hartmut, Ochs, Hans D., Cunningham-Rundles, Charlotte, Vinh, Donald C., Kiessling, Peter, Greve, Bernhard, Jolles, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier Inc. on behalf of the American Academy of Allergy, Asthma & Immunology. 2020
Materias:
Reviews and Feature Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471860/
https://www.ncbi.nlm.nih.gov/pubmed/32896308
http://dx.doi.org/10.1016/j.jaci.2020.07.016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471860/
https://www.ncbi.nlm.nih.gov/pubmed/32896308
http://dx.doi.org/10.1016/j.jaci.2020.07.016

Ejemplares similares