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Targeting FcRn for immunomodulation: Benefits, risks, and practical considerations
The neonatal fragment crystallizable (Fc) receptor (FcRn) functions as a recycling mechanism to prevent degradation and extend the half-life of IgG and albumin in the circulation. Several FcRn inhibitors selectively targeting IgG recycling are now moving rapidly toward clinical practice in neurology...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Authors. Published by Elsevier Inc. on behalf of the American Academy of Allergy, Asthma & Immunology.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471860/ https://www.ncbi.nlm.nih.gov/pubmed/32896308 http://dx.doi.org/10.1016/j.jaci.2020.07.016 |