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Stabilization of human telomeric RNA G-quadruplex by the water-compatible optically pure and biologically-active metallohelices
RNA G-quadruplexes have been suggested to play key roles in fundamental biological processes and are linked to human diseases. Thus, they also represent good potential therapeutic targets. Here, we describe, using the methods of molecular biophysics, interactions of a series of biologically-active s...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471899/ https://www.ncbi.nlm.nih.gov/pubmed/32884069 http://dx.doi.org/10.1038/s41598-020-71429-5 |