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Characterization of basigin monoclonal antibodies for receptor-mediated drug delivery to the brain

The brain uptake of biotherapeutics for brain diseases is hindered by the blood–brain barrier (BBB). The BBB selectively regulates the transport of large molecules into the brain and thereby maintains brain homeostasis. Receptor-mediated transcytosis (RMT) is one mechanism to deliver essential prote...

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Detalles Bibliográficos
Autores principales:	Christensen, Sarah Christine, Krogh, Berit Olsen, Jensen, Allan, Andersen, Christian Brix Folsted, Christensen, Søren, Nielsen, Morten Schallburg
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7471916/ https://www.ncbi.nlm.nih.gov/pubmed/32884039 http://dx.doi.org/10.1038/s41598-020-71286-2

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