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A CRISPR/Cas9 Generated Bovine CD46-knockout Cell Line—A Tool to Elucidate the Adaptability of Bovine Viral Diarrhea Viruses (BVDV)

Bovine viral diarrhea virus (BVDV) entry into a host cell is mediated by the interaction of the viral glycoprotein E2 with the cellular transmembrane CD46 receptor. In this study, we generated a stable Madin–Darby Bovine Kidney (MDBK) CD46-knockout cell line to study the ability of different pestivi...

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Detalles Bibliográficos
Autores principales:	Szillat, Kevin P., Koethe, Susanne, Wernike, Kerstin, Höper, Dirk, Beer, Martin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7472008/ https://www.ncbi.nlm.nih.gov/pubmed/32781607 http://dx.doi.org/10.3390/v12080859

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