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Efficient Non-Epigenetic Activation of HIV Latency through the T-Cell Receptor Signalosome

Human immunodeficiency virus type-1 (HIV-1) can either undergo a lytic pathway to cause productive systemic infections or enter a latent state in which the integrated provirus remains transcriptionally silent for decades. The ability to latently infect T-cells enables HIV-1 to establish persistent i...

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Detalles Bibliográficos
Autores principales: Hokello, Joseph, Sharma, Adhikarimayum Lakhikumar, Tyagi, Mudit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7472175/
https://www.ncbi.nlm.nih.gov/pubmed/32784426
http://dx.doi.org/10.3390/v12080868