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Thermal Characterization of Phantoms Used for Quality Assurance of Deep Hyperthermia Systems

Tissue mimicking phantoms are frequently used in hyperthermia applications for device and protocol optimization. Unfortunately, a commonly experienced limitation is that their precise thermal properties are not available. Therefore, in this study, the thermal properties of three currently used QA ph...

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Detalles Bibliográficos
Autores principales: Farina, Laura, Sumser, Kemal, van Rhoon, Gerard, Curto, Sergio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7472229/
https://www.ncbi.nlm.nih.gov/pubmed/32823788
http://dx.doi.org/10.3390/s20164549
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author Farina, Laura
Sumser, Kemal
van Rhoon, Gerard
Curto, Sergio
author_facet Farina, Laura
Sumser, Kemal
van Rhoon, Gerard
Curto, Sergio
author_sort Farina, Laura
collection PubMed
description Tissue mimicking phantoms are frequently used in hyperthermia applications for device and protocol optimization. Unfortunately, a commonly experienced limitation is that their precise thermal properties are not available. Therefore, in this study, the thermal properties of three currently used QA phantoms for deep hyperthermia are measured with an “off-shelf” commercial thermal property analyzer. We have measured averaged values of thermal conductivity (k = 0.59 ± 0.07 Wm(−1)K(−1)), volumetric heat capacity (C = 3.85 ± 0.45 MJm(−3)K(−1)) and thermal diffusivity (D = 0.16 ± 0.02 mm(2)s(−1)). These values are comparable with reported values of internal organs, such as liver, kidney and muscle. In addition, a sensitivity study of the performance of the commercial sensor is conducted. To ensure correct thermal measurements, the sample under test should entirely cover the length of the sensor, and a minimum of 4 mm of material parallel to the sensor in all directions should be guaranteed.
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spelling pubmed-74722292020-09-04 Thermal Characterization of Phantoms Used for Quality Assurance of Deep Hyperthermia Systems Farina, Laura Sumser, Kemal van Rhoon, Gerard Curto, Sergio Sensors (Basel) Article Tissue mimicking phantoms are frequently used in hyperthermia applications for device and protocol optimization. Unfortunately, a commonly experienced limitation is that their precise thermal properties are not available. Therefore, in this study, the thermal properties of three currently used QA phantoms for deep hyperthermia are measured with an “off-shelf” commercial thermal property analyzer. We have measured averaged values of thermal conductivity (k = 0.59 ± 0.07 Wm(−1)K(−1)), volumetric heat capacity (C = 3.85 ± 0.45 MJm(−3)K(−1)) and thermal diffusivity (D = 0.16 ± 0.02 mm(2)s(−1)). These values are comparable with reported values of internal organs, such as liver, kidney and muscle. In addition, a sensitivity study of the performance of the commercial sensor is conducted. To ensure correct thermal measurements, the sample under test should entirely cover the length of the sensor, and a minimum of 4 mm of material parallel to the sensor in all directions should be guaranteed. MDPI 2020-08-13 /pmc/articles/PMC7472229/ /pubmed/32823788 http://dx.doi.org/10.3390/s20164549 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Farina, Laura
Sumser, Kemal
van Rhoon, Gerard
Curto, Sergio
Thermal Characterization of Phantoms Used for Quality Assurance of Deep Hyperthermia Systems
title Thermal Characterization of Phantoms Used for Quality Assurance of Deep Hyperthermia Systems
title_full Thermal Characterization of Phantoms Used for Quality Assurance of Deep Hyperthermia Systems
title_fullStr Thermal Characterization of Phantoms Used for Quality Assurance of Deep Hyperthermia Systems
title_full_unstemmed Thermal Characterization of Phantoms Used for Quality Assurance of Deep Hyperthermia Systems
title_short Thermal Characterization of Phantoms Used for Quality Assurance of Deep Hyperthermia Systems
title_sort thermal characterization of phantoms used for quality assurance of deep hyperthermia systems
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7472229/
https://www.ncbi.nlm.nih.gov/pubmed/32823788
http://dx.doi.org/10.3390/s20164549
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