Primary Human Derived Blood Outgrowth Endothelial Cells: An Appropriate In Vitro Model to Study Shiga Toxin Mediated Damage of Endothelial Cells

Hemolytic uremic syndrome (HUS) is a rare disease primarily characterized by hemolytic anemia, thrombocytopenia, and acute renal failure. Endothelial damage is the hallmark of the pathogenesis of HUS with an infection with the Shiga toxin (Stx) producing Escherichia coli (STEC-HUS) as the main under...

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Detalles Bibliográficos
Autores principales: Feitz, Wouter J. C., van de Kar, Nicole C. A. J., Cheong, Ian, van der Velden, Thea J. A. M., Ortiz-Sandoval, Carolina G., Orth-Höller, Dorothea, van den Heuvel, Lambert P. J. W., Licht, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7472281/
https://www.ncbi.nlm.nih.gov/pubmed/32751286
http://dx.doi.org/10.3390/toxins12080483

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