Dengue: A Minireview

Dengue, caused by infection of any of four dengue virus serotypes (DENV-1 to DENV-4), is a mosquito-borne disease of major public health concern associated with significant morbidity, mortality, and economic cost, particularly in developing countries. Dengue incidence has increased 30-fold in the la...

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Detalles Bibliográficos
Autores principales: Harapan, Harapan, Michie, Alice, Sasmono, R. Tedjo, Imrie, Allison
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7472303/
https://www.ncbi.nlm.nih.gov/pubmed/32751561
http://dx.doi.org/10.3390/v12080829
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author Harapan, Harapan
Michie, Alice
Sasmono, R. Tedjo
Imrie, Allison
author_facet Harapan, Harapan
Michie, Alice
Sasmono, R. Tedjo
Imrie, Allison
author_sort Harapan, Harapan
collection PubMed
description Dengue, caused by infection of any of four dengue virus serotypes (DENV-1 to DENV-4), is a mosquito-borne disease of major public health concern associated with significant morbidity, mortality, and economic cost, particularly in developing countries. Dengue incidence has increased 30-fold in the last 50 years and over 50% of the world’s population, in more than 100 countries, live in areas at risk of DENV infection. We reviews DENV biology, epidemiology, transmission dynamics including circulating serotypes and genotypes, the immune response, the pathogenesis of the disease as well as updated diagnostic methods, treatments, vector control and vaccine developments.
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spelling pubmed-74723032020-09-04 Dengue: A Minireview Harapan, Harapan Michie, Alice Sasmono, R. Tedjo Imrie, Allison Viruses Review Dengue, caused by infection of any of four dengue virus serotypes (DENV-1 to DENV-4), is a mosquito-borne disease of major public health concern associated with significant morbidity, mortality, and economic cost, particularly in developing countries. Dengue incidence has increased 30-fold in the last 50 years and over 50% of the world’s population, in more than 100 countries, live in areas at risk of DENV infection. We reviews DENV biology, epidemiology, transmission dynamics including circulating serotypes and genotypes, the immune response, the pathogenesis of the disease as well as updated diagnostic methods, treatments, vector control and vaccine developments. MDPI 2020-07-30 /pmc/articles/PMC7472303/ /pubmed/32751561 http://dx.doi.org/10.3390/v12080829 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Harapan, Harapan
Michie, Alice
Sasmono, R. Tedjo
Imrie, Allison
Dengue: A Minireview
title Dengue: A Minireview
title_full Dengue: A Minireview
title_fullStr Dengue: A Minireview
title_full_unstemmed Dengue: A Minireview
title_short Dengue: A Minireview
title_sort dengue: a minireview
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7472303/
https://www.ncbi.nlm.nih.gov/pubmed/32751561
http://dx.doi.org/10.3390/v12080829
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