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Bicuspid Aortic Valve and Endothelial Dysfunction: Current Evidence and Potential Therapeutic Targets

Bicuspid aortic valve (BAV), the most frequent congenital heart malformation, is characterized by the presence of a two-leaflet aortic valve instead of a three-leaflet one. BAV disease progression is associated with valvular dysfunction (in the form of stenosis or regurgitation) and aortopathy, whic...

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Detalles Bibliográficos
Autores principales: Antequera-González, Borja, Martínez-Micaelo, Neus, Alegret, Josep M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7472870/
https://www.ncbi.nlm.nih.gov/pubmed/32973551
http://dx.doi.org/10.3389/fphys.2020.01015