Polyphenolic Proanthocyanidin-B2 suppresses proliferation of liver cancer cells and hepatocellular carcinogenesis through directly binding and inhibiting AKT activity

The well-documented anticarcinogenic properties of natural polyphenolic proanthocyanidins (OPC) have been primarily attributed to their antioxidant and anti-inflammatory potency. Emerging evidence suggests that OPC may target canonical oncogenic pathways, including PI3K/AKT; however, the underlying...

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Detalles Bibliográficos
Autores principales: Liu, Guijun, Shi, Aimin, Wang, Ningning, Li, Min, He, Xuxiao, Yin, Chunzhao, Tu, Qiaochu, Shen, Xia, Tao, Yongzhen, Wang, Qiang, Yin, Huiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7472926/
https://www.ncbi.nlm.nih.gov/pubmed/32863234
http://dx.doi.org/10.1016/j.redox.2020.101701

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