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FcRn Overexpression Expands Diversity of the Humoral Immune Response in bFcRn Transgenic Mice

The neonatal Fc receptor (FcRn) plays key roles in IgG and albumin homeostasis, maternal IgG transport, and antigen presentation of IgG-opsonized antigens. Previously, we reported that transgenic (Tg) mice that overexpress bovine FcRn (bFcRn) have augmented T-dependent humoral immune response with i...

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Detalles Bibliográficos
Autores principales: Szikora, Bence, Marx, Anita, Jani, Péter K., Pipek, Orsolya, Müller, Viktor, Csabai, István, Kacskovics, Imre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7472951/
https://www.ncbi.nlm.nih.gov/pubmed/32973781
http://dx.doi.org/10.3389/fimmu.2020.01887

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