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Indomethacin Increases the Efficacy of Oxygen Utilization of Colonic Mitochondria and Uncouples Hepatic Mitochondria in Tissue Homogenates From Healthy Rats

Background: Studies suggest that indomethacin (Indo) exhibits detrimental changes in the small intestine (microvascular disorder, villus shortening, and epithelial disruption), mainly due to mitochondrial uncoupling. The effects of Indo on colon and liver tissue are unclear. The aim of this study wa...

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Detalles Bibliográficos
Autores principales: Herminghaus, Anna, Buitenhuis, Albert J., Schulz, Jan, Truse, Richard, Vollmer, Christian, Relja, Borna, Bauer, Inge, Picker, Olaf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7472952/
https://www.ncbi.nlm.nih.gov/pubmed/32974368
http://dx.doi.org/10.3389/fmed.2020.00463

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