COVID-19 Makes B Cells Forget, but T Cells Remember

Understanding which arms of the immune response are responsible for protection against SARS-CoV-2 infection is key to predicting long-term immunity and to inform vaccine design. Two studies in this issue of Cell collectively suggest that, although SARS-CoV-2 infection may blunt long-lived antibody r...

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Autores principales: Cañete, Pablo F., Vinuesa, Carola G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2020
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7472965/
https://www.ncbi.nlm.nih.gov/pubmed/32976799
http://dx.doi.org/10.1016/j.cell.2020.09.013
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author Cañete, Pablo F.
Vinuesa, Carola G.
author_facet Cañete, Pablo F.
Vinuesa, Carola G.
author_sort Cañete, Pablo F.
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description Understanding which arms of the immune response are responsible for protection against SARS-CoV-2 infection is key to predicting long-term immunity and to inform vaccine design. Two studies in this issue of Cell collectively suggest that, although SARS-CoV-2 infection may blunt long-lived antibody responses, immune memory might still be achieved through virus-specific memory T cells.
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spelling pubmed-74729652020-09-08 COVID-19 Makes B Cells Forget, but T Cells Remember Cañete, Pablo F. Vinuesa, Carola G. Cell Preview Understanding which arms of the immune response are responsible for protection against SARS-CoV-2 infection is key to predicting long-term immunity and to inform vaccine design. Two studies in this issue of Cell collectively suggest that, although SARS-CoV-2 infection may blunt long-lived antibody responses, immune memory might still be achieved through virus-specific memory T cells. Elsevier Inc. 2020-10-01 2020-09-04 /pmc/articles/PMC7472965/ /pubmed/32976799 http://dx.doi.org/10.1016/j.cell.2020.09.013 Text en © 2020 Elsevier Inc. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Preview
Cañete, Pablo F.
Vinuesa, Carola G.
COVID-19 Makes B Cells Forget, but T Cells Remember
title COVID-19 Makes B Cells Forget, but T Cells Remember
title_full COVID-19 Makes B Cells Forget, but T Cells Remember
title_fullStr COVID-19 Makes B Cells Forget, but T Cells Remember
title_full_unstemmed COVID-19 Makes B Cells Forget, but T Cells Remember
title_short COVID-19 Makes B Cells Forget, but T Cells Remember
title_sort covid-19 makes b cells forget, but t cells remember
topic Preview
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7472965/
https://www.ncbi.nlm.nih.gov/pubmed/32976799
http://dx.doi.org/10.1016/j.cell.2020.09.013
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