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Biobanking for Translational Diabetes Research in India
India is declared as the diabetic capital of the world. Clinically well-annotated blood samples will advance diabetes research for better diagnostic and treatment methods. Building a disease-specific biobank with high-quality peripheral blood mononuclear cells (PBMCs) and clinical follow-up data sys...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mary Ann Liebert, Inc., publishers
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7473039/ https://www.ncbi.nlm.nih.gov/pubmed/32908805 http://dx.doi.org/10.1089/biores.2019.0052 |
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author | Gangadharan, Charitha Wills, Soniya Vangala, Rajani Kanth Sigamani, Alben |
author_facet | Gangadharan, Charitha Wills, Soniya Vangala, Rajani Kanth Sigamani, Alben |
author_sort | Gangadharan, Charitha |
collection | PubMed |
description | India is declared as the diabetic capital of the world. Clinically well-annotated blood samples will advance diabetes research for better diagnostic and treatment methods. Building a disease-specific biobank with high-quality peripheral blood mononuclear cells (PBMCs) and clinical follow-up data system will serve as a good platform for clinical research in diabetes. Processing and storage of high-quality biospecimen for translational research in diabetes demand the implementation of good clinical laboratory practices. “Certification or accreditation programs” that improve biorepository processes and frameworks are lacking in Indian context. To sustain and translate the research into clinical practice, good governance of the biobank and financial resources is required. For ethical issues related to health needs of the people and participants in the research, issues related to research process, translational research, and commercialization, data sharing should be addressed. For India to be an innovation and sustainable country Indian government is supporting translational research facilities, including biobanks. India has developed biobanks for various diseases; however, diabetes-specific research biorepository is lacking. Given the dangers of diabetic burden, India should set up a diabetes disease-specific repository learning from the global organizations and customize to the needs of Indian context. It is important to have private agencies get involved to develop biobanks and future research as there are commercial goals to translate research into practice. New technologies of specimen storing and preservation, data management, and data sharing should be adopted for developing cost-effective long-standing disease-specific population biobank in India. |
format | Online Article Text |
id | pubmed-7473039 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Mary Ann Liebert, Inc., publishers |
record_format | MEDLINE/PubMed |
spelling | pubmed-74730392020-09-08 Biobanking for Translational Diabetes Research in India Gangadharan, Charitha Wills, Soniya Vangala, Rajani Kanth Sigamani, Alben Biores Open Access Literature Review India is declared as the diabetic capital of the world. Clinically well-annotated blood samples will advance diabetes research for better diagnostic and treatment methods. Building a disease-specific biobank with high-quality peripheral blood mononuclear cells (PBMCs) and clinical follow-up data system will serve as a good platform for clinical research in diabetes. Processing and storage of high-quality biospecimen for translational research in diabetes demand the implementation of good clinical laboratory practices. “Certification or accreditation programs” that improve biorepository processes and frameworks are lacking in Indian context. To sustain and translate the research into clinical practice, good governance of the biobank and financial resources is required. For ethical issues related to health needs of the people and participants in the research, issues related to research process, translational research, and commercialization, data sharing should be addressed. For India to be an innovation and sustainable country Indian government is supporting translational research facilities, including biobanks. India has developed biobanks for various diseases; however, diabetes-specific research biorepository is lacking. Given the dangers of diabetic burden, India should set up a diabetes disease-specific repository learning from the global organizations and customize to the needs of Indian context. It is important to have private agencies get involved to develop biobanks and future research as there are commercial goals to translate research into practice. New technologies of specimen storing and preservation, data management, and data sharing should be adopted for developing cost-effective long-standing disease-specific population biobank in India. Mary Ann Liebert, Inc., publishers 2020-08-19 /pmc/articles/PMC7473039/ /pubmed/32908805 http://dx.doi.org/10.1089/biores.2019.0052 Text en © Charitha Gangadharan et al., 2020; Published by Mary Ann Liebert, Inc. This Open Access article is distributed under the terms of the Creative Commons License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Literature Review Gangadharan, Charitha Wills, Soniya Vangala, Rajani Kanth Sigamani, Alben Biobanking for Translational Diabetes Research in India |
title | Biobanking for Translational Diabetes Research in India |
title_full | Biobanking for Translational Diabetes Research in India |
title_fullStr | Biobanking for Translational Diabetes Research in India |
title_full_unstemmed | Biobanking for Translational Diabetes Research in India |
title_short | Biobanking for Translational Diabetes Research in India |
title_sort | biobanking for translational diabetes research in india |
topic | Literature Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7473039/ https://www.ncbi.nlm.nih.gov/pubmed/32908805 http://dx.doi.org/10.1089/biores.2019.0052 |
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