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Pacientes críticos COVID-19 atendidos por anestesiólogos en el Noroeste de España: estudio multicéntrico, prospectivo, observacional

BACKGROUND AND OBJECTIVES: There are limited information on outcome, complications and treatments of critically ill COVID-19 patients requiring admission to an intensive care unit (ICU). The aim of this study is to describe the clinical ICU course, treatments used, complications and outcomes, of cri...

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Autores principales: Taboada, M., Rama, P., Pita-Romero, R., Moreno, E., Leal, S., Varela, M., Cid, M., Caruezo, V., Alvarado de la Torre, S., Corujeira, M., Sarmiento, A., Domínguez, B., Diaz, P., Cánovas, L., López Sánchez, M., Vilas, E., Rodríguez, A., Freire, L., Domínguez, S., Baluja, A., Atanassoff, P.G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedad Española de Anestesiología, Reanimación y Terapéutica del Dolor. Published by Elsevier España, S.L.U. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7473389/
https://www.ncbi.nlm.nih.gov/pubmed/33077309
http://dx.doi.org/10.1016/j.redar.2020.08.004
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author Taboada, M.
Rama, P.
Pita-Romero, R.
Moreno, E.
Leal, S.
Varela, M.
Cid, M.
Caruezo, V.
Alvarado de la Torre, S.
Corujeira, M.
Sarmiento, A.
Domínguez, B.
Diaz, P.
Cánovas, L.
López Sánchez, M.
Vilas, E.
Rodríguez, A.
Freire, L.
Domínguez, S.
Baluja, A.
Atanassoff, P.G.
author_facet Taboada, M.
Rama, P.
Pita-Romero, R.
Moreno, E.
Leal, S.
Varela, M.
Cid, M.
Caruezo, V.
Alvarado de la Torre, S.
Corujeira, M.
Sarmiento, A.
Domínguez, B.
Diaz, P.
Cánovas, L.
López Sánchez, M.
Vilas, E.
Rodríguez, A.
Freire, L.
Domínguez, S.
Baluja, A.
Atanassoff, P.G.
author_sort Taboada, M.
collection PubMed
description BACKGROUND AND OBJECTIVES: There are limited information on outcome, complications and treatments of critically ill COVID-19 patients requiring admission to an intensive care unit (ICU). The aim of this study is to describe the clinical ICU course, treatments used, complications and outcomes, of critically ill COVID-19 patients admitted in seven ICU in Galicia region during the 2020 March-April pandemic peak. METHODS: Between March 21 and April 19, 2020, we evaluated critically ill COVID-19 patients admitted to the ICU of Anesthesia of seven hospitals in Galicia, northwestern Spain. Outcome, complications, and treatments were monitored until May 6, 2020, the final date of follow-up. RESULTS: A total of 97 critically ill COVID-19 patients were included. During ICU stay, mechanical ventilation became necessary in 80 (82.5%) patients, and tracheostomy in 22 (22.7%) patients. Prone position was used frequently in both intubated (67.5%) and awake (27.8%) patients. Medications consisted of antivirals agents (92.7%), corticosteroids (93.8%), tocilizumab (57.7%), and intermediate or high doses of anticoagulants (83.5%). The most frequent complications were ICU-acquired infection (52.6%), thrombosis events (16.5%), and reintubation (9.3%). After a median follow-up of 42 (34-45) days, 15 patients (15.5%) deceased, 73 patients (75.2%) had been discharged from ICU, and nine patients (9.3%) were still in the ICU. CONCLUSIONS: A high proportion of our critically ill COVID-19 patients required mechanical ventilation, prone positioning, antiviral medication, corticosteroids, and anticoagulants. ICU complications were frequent, mainly infections and thrombotic events. We had a relatively low mortality of 15,5%.
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spelling pubmed-74733892020-09-08 Pacientes críticos COVID-19 atendidos por anestesiólogos en el Noroeste de España: estudio multicéntrico, prospectivo, observacional Taboada, M. Rama, P. Pita-Romero, R. Moreno, E. Leal, S. Varela, M. Cid, M. Caruezo, V. Alvarado de la Torre, S. Corujeira, M. Sarmiento, A. Domínguez, B. Diaz, P. Cánovas, L. López Sánchez, M. Vilas, E. Rodríguez, A. Freire, L. Domínguez, S. Baluja, A. Atanassoff, P.G. Rev Esp Anestesiol Reanim Original BACKGROUND AND OBJECTIVES: There are limited information on outcome, complications and treatments of critically ill COVID-19 patients requiring admission to an intensive care unit (ICU). The aim of this study is to describe the clinical ICU course, treatments used, complications and outcomes, of critically ill COVID-19 patients admitted in seven ICU in Galicia region during the 2020 March-April pandemic peak. METHODS: Between March 21 and April 19, 2020, we evaluated critically ill COVID-19 patients admitted to the ICU of Anesthesia of seven hospitals in Galicia, northwestern Spain. Outcome, complications, and treatments were monitored until May 6, 2020, the final date of follow-up. RESULTS: A total of 97 critically ill COVID-19 patients were included. During ICU stay, mechanical ventilation became necessary in 80 (82.5%) patients, and tracheostomy in 22 (22.7%) patients. Prone position was used frequently in both intubated (67.5%) and awake (27.8%) patients. Medications consisted of antivirals agents (92.7%), corticosteroids (93.8%), tocilizumab (57.7%), and intermediate or high doses of anticoagulants (83.5%). The most frequent complications were ICU-acquired infection (52.6%), thrombosis events (16.5%), and reintubation (9.3%). After a median follow-up of 42 (34-45) days, 15 patients (15.5%) deceased, 73 patients (75.2%) had been discharged from ICU, and nine patients (9.3%) were still in the ICU. CONCLUSIONS: A high proportion of our critically ill COVID-19 patients required mechanical ventilation, prone positioning, antiviral medication, corticosteroids, and anticoagulants. ICU complications were frequent, mainly infections and thrombotic events. We had a relatively low mortality of 15,5%. Sociedad Española de Anestesiología, Reanimación y Terapéutica del Dolor. Published by Elsevier España, S.L.U. 2021-01 2020-09-04 /pmc/articles/PMC7473389/ /pubmed/33077309 http://dx.doi.org/10.1016/j.redar.2020.08.004 Text en © 2020 Sociedad Española de Anestesiología, Reanimación y Terapéutica del Dolor. Published by Elsevier España, S.L.U. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Original
Taboada, M.
Rama, P.
Pita-Romero, R.
Moreno, E.
Leal, S.
Varela, M.
Cid, M.
Caruezo, V.
Alvarado de la Torre, S.
Corujeira, M.
Sarmiento, A.
Domínguez, B.
Diaz, P.
Cánovas, L.
López Sánchez, M.
Vilas, E.
Rodríguez, A.
Freire, L.
Domínguez, S.
Baluja, A.
Atanassoff, P.G.
Pacientes críticos COVID-19 atendidos por anestesiólogos en el Noroeste de España: estudio multicéntrico, prospectivo, observacional
title Pacientes críticos COVID-19 atendidos por anestesiólogos en el Noroeste de España: estudio multicéntrico, prospectivo, observacional
title_full Pacientes críticos COVID-19 atendidos por anestesiólogos en el Noroeste de España: estudio multicéntrico, prospectivo, observacional
title_fullStr Pacientes críticos COVID-19 atendidos por anestesiólogos en el Noroeste de España: estudio multicéntrico, prospectivo, observacional
title_full_unstemmed Pacientes críticos COVID-19 atendidos por anestesiólogos en el Noroeste de España: estudio multicéntrico, prospectivo, observacional
title_short Pacientes críticos COVID-19 atendidos por anestesiólogos en el Noroeste de España: estudio multicéntrico, prospectivo, observacional
title_sort pacientes críticos covid-19 atendidos por anestesiólogos en el noroeste de españa: estudio multicéntrico, prospectivo, observacional
topic Original
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7473389/
https://www.ncbi.nlm.nih.gov/pubmed/33077309
http://dx.doi.org/10.1016/j.redar.2020.08.004
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