Cargando…

Development and evaluation of next-generation cardiotoxicity assay based on embryonic stem cell-derived cardiomyocytes

In accordance with requirements of the ICH S7B safety pharma-cology guidelines, numerous next-generation cardiotoxicity studies using human stem cell-derived cardiomyocytes (CMs) are being conducted globally. Although several stem cell-derived CMs are being developed for commercialization, there is...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ryu, Bokyeong, Choi, Seong Woo, Lee, Seul-Gi, Jeong, Young-Hoon, Kim, Ukjin, Kim, Jin, Jung, Cho-Rok, Chung, Hyung-Min, Park, Jae-Hak, Kim, C-Yoon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Biochemistry and Molecular Biology 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7473479/ https://www.ncbi.nlm.nih.gov/pubmed/32336319 http://dx.doi.org/10.5483/BMBRep.2020.53.8.022

Ejemplares similares

Next-Generation Intestinal Toxicity Model of Human Embryonic Stem Cell-Derived Enterocyte-Like Cells
por: Ryu, Bokyeong, et al.
Publicado: (2021)

Vitrification for cryopreservation of 2D and 3D stem cells culture using high concentration of cryoprotective agents
por: Jeong, Young-Hoon, et al.
Publicado: (2020)

Pimozide Inhibits the Human Prostate Cancer Cells Through the Generation of Reactive Oxygen Species
por: Kim, Ukjin, et al.
Publicado: (2020)

Cardiotoxicity induced by the combination therapy of chloroquine and azithromycin in human embryonic stem cell-derived cardiomyocytes
por: Kim, Ye Seul, et al.
Publicado: (2020)

Improved human hematopoietic reconstitution in HepaRG co-transplanted humanized NSG mice
por: Kim, Jin, et al.
Publicado: (2020)

Use of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes to Predict the Cardiotoxicity Potential of Next Generation Nicotine Products
por: Simms, Liam, et al.
Publicado: (2022)

Immunomodulation of Pluripotent Stem Cell-Derived Mesenchymal Stem Cells in Rotator Cuff Tears Model
por: Baek, Jieun, et al.
Publicado: (2022)

Cardiotoxicity evaluation using human embryonic stem cells and induced pluripotent stem cell-derived cardiomyocytes
por: Zhao, Qi, et al.
Publicado: (2017)

BAPTA, a calcium chelator, neuroprotects injured neurons in vitro and promotes motor recovery after spinal cord transection in vivo
por: Kang, Kyu‐ree, et al.
Publicado: (2021)

Tomatidine-stimulated maturation of human embryonic stem cell-derived cardiomyocytes for modeling mitochondrial dysfunction
por: Kim, Ye Seul, et al.
Publicado: (2022)

Anti-Inflammatory Effects of M-MSCs in DNCB-Induced Atopic Dermatitis Mice
por: Ryu, Bokyeong, et al.
Publicado: (2020)

Echinochrome A Protects Mitochondrial Function in Cardiomyocytes against Cardiotoxic Drugs
por: Jeong, Seung Hun, et al.
Publicado: (2014)

Electrophysiological mechanisms of vandetanib-induced cardiotoxicity: Comparison of action potentials in rabbit Purkinje fibers and pluripotent stem cell-derived cardiomyocytes
por: Lee, Hyang-Ae, et al.
Publicado: (2018)

Next Generation Ceramic Substrate Fabricated at Room Temperature
por: Kim, Yuna, et al.
Publicado: (2017)

Establishment of Neurotoxicity Assessment Using Microelectrode Array (MEA) with hiPSC-Derived Neurons and Evaluation of New Psychoactive Substances (NPS)
por: Kang, Kyu-ree, et al.
Publicado: (2022)

Epigenetic Regulation of Cardiomyocyte Differentiation from Embryonic and Induced Pluripotent Stem Cells
por: Kim, Yong-Jin, et al.
Publicado: (2021)

Molecular Mechanisms of Cardiomyocyte Death in Drug-Induced Cardiotoxicity
por: Ma, Wanjun, et al.
Publicado: (2020)

Cardiomyocyte Atrophy, an Underestimated Contributor in Doxorubicin-Induced Cardiotoxicity
por: Chen, De-Shu, et al.
Publicado: (2022)

Chronic Cardiotoxicity Assays Using Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes (hiPSC-CMs)
por: Narkar, Akshay, et al.
Publicado: (2022)

Modeling Doxorubicin-Induced Cardiotoxicity in Human Pluripotent Stem Cell Derived-Cardiomyocytes
por: Maillet, Agnes, et al.
Publicado: (2016)

Exogenous 8-hydroxydeoxyguanosine attenuates doxorubicin-induced cardiotoxicity by decreasing pyroptosis in H9c2 cardiomyocytes
por: Hwang, Soyoung, et al.
Publicado: (2022)

Fluorescent hiPSC-derived MYH6-mScarlet cardiomyocytes for real-time tracking, imaging, and cardiotoxicity assays
por: Maria Cherian, Reeja, et al.
Publicado: (2022)

Bioactive Lipid O-cyclic phytosphingosine-1-phosphate Promotes Differentiation of Human Embryonic Stem Cells into Cardiomyocytes via ALK3/BMPR Signaling
por: Jang, Ji-Hye, et al.
Publicado: (2021)

Micro-Arrayed Human Embryonic Stem Cells-Derived Cardiomyocytes for In Vitro Functional Assay
por: Serena, Elena, et al.
Publicado: (2012)

Antipsychotics cardiotoxicity: What's known and what's next
por: Li, Xiao-Qing, et al.
Publicado: (2021)

Sublethal Caspase Activation Promotes Generation of Cardiomyocytes from Embryonic Stem Cells
por: Bulatovic, Ivana, et al.
Publicado: (2015)

Next-generation transcatheter aortic valve implantation
por: Lim, Hong-Gook, et al.
Publicado: (2020)

Improved Transfection Efficiency and Metabolic Activity in Human Embryonic Stem Cell Using Non-Enzymatic Method
por: Kim, C-Yoon, et al.
Publicado: (2018)

RDA-Genebank and Digital Phenotyping for Next-Generation Research on Plant Genetic Resources
por: Kim, Seong-Hoon, et al.
Publicado: (2023)

Isolation of Embryonic Cardiomyocytes and Cell Proliferation Assay Using Genetically Engineered Reporter Mouse Model
por: Beall, Maren C., et al.
Publicado: (2023)

Efficient generation of transgenic cattle using the DNA transposon and their analysis by next-generation sequencing
por: Yum, Soo-Young, et al.
Publicado: (2016)

Mirogabalin: could it be the next generation gabapentin or pregabalin?
por: Kim, Jae-Yeon, et al.
Publicado: (2021)

Role of the epithelial–mesenchymal transition and its effects on embryonic stem cells
por: Kim, Ye-Seul, et al.
Publicado: (2014)

Cdo Is Required for Efficient Motor Neuron Generation of Embryonic Stem Cells
por: Kim, Hyebeen, et al.
Publicado: (2020)

Development of Genome-Wide SSR Markers from Angelica gigas Nakai Using Next Generation Sequencing
por: Gil, Jinsu, et al.
Publicado: (2017)

Effect of Cell Labeling on the Function of Human Pluripotent Stem Cell-Derived Cardiomyocytes
por: Choi, Seong Woo, et al.
Publicado: (2020)

Identification and Characterization of MicroRNAs in Normal Equine Tissues by Next Generation Sequencing
por: Kim, Myung-Chul, et al.
Publicado: (2014)

The Stack Optimization of Magnetic Heterojunction Structures for Next-Generation Spintronic Logic Applications
por: Cho, Jaehun, et al.
Publicado: (2023)

Virulence factors released from Porphyromonas gingivalis induce electrophysiological dysfunction in human pluripotent stem cell-derived cardiomyocytes
por: Heo, Soon Chul, et al.
Publicado: (2022)

Cardiomyocyte-specific disruption of Cathepsin K protects against doxorubicin-induced cardiotoxicity
por: Guo, Rui, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_o4mth8psk65lrfurg1fhmg5o4e