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Gluconeogenesis and PEPCK are critical components of healthy aging and dietary restriction life extension
High glucose diets are unhealthy, although the mechanisms by which elevated glucose is harmful to whole animal physiology are not well understood. In Caenorhabditis elegans, high glucose shortens lifespan, while chemically inflicted glucose restriction promotes longevity. We investigated the impact...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7473531/ https://www.ncbi.nlm.nih.gov/pubmed/32841230 http://dx.doi.org/10.1371/journal.pgen.1008982 |