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Chest computed tomography (CT) findings and semiquantitative scoring of 60 patients with coronavirus disease 2019 (COVID-19): A retrospective imaging analysis combining anatomy and pathology

In this study, we ascertained the chest CT data of 60 patients admitted to 3 hospitals in Chongqing with confirmed COVID-19. We conducted anatomical and pathological analyses to elucidate the possible reasons for the distribution, morphology, and characteristics of COVID-19 in chest CT. We also shar...

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Autores principales: Zhang, Hao, Jiang, Xu-jing, Liu, Xiao-hua, Ma, Hong, Zhang, Ya-hong, Rao, Yue, Li, Lin, Xu, Hai-yan, Lyu, Fa-jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7473568/
https://www.ncbi.nlm.nih.gov/pubmed/32886711
http://dx.doi.org/10.1371/journal.pone.0238760
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author Zhang, Hao
Jiang, Xu-jing
Liu, Xiao-hua
Ma, Hong
Zhang, Ya-hong
Rao, Yue
Li, Lin
Xu, Hai-yan
Lyu, Fa-jin
author_facet Zhang, Hao
Jiang, Xu-jing
Liu, Xiao-hua
Ma, Hong
Zhang, Ya-hong
Rao, Yue
Li, Lin
Xu, Hai-yan
Lyu, Fa-jin
author_sort Zhang, Hao
collection PubMed
description In this study, we ascertained the chest CT data of 60 patients admitted to 3 hospitals in Chongqing with confirmed COVID-19. We conducted anatomical and pathological analyses to elucidate the possible reasons for the distribution, morphology, and characteristics of COVID-19 in chest CT. We also shared a semiquantitative scoring of affected lung segments, which was recommended by our local medical association. This scoring system was applied to quantify the severity of the disease. The most frequent imaging findings of COVID-19 were subpleural ground glass opacities and consolidation; there was a significant difference in semiquantitative scores between the early, progressive, and severe stages of the disease. We conclude that the chest CT findings of COVID-19 showed certain characteristics because of the anatomical features of the human body and pathological changes caused by the virus. Therefore, chest CT is a valuable tool for facilitating the diagnosis of COVID-19 and semiquantitative scoring of affected lung segments may further elucidate diagnosis and assessment of disease severity. This will assist healthcare workers in diagnosing COVID-19 and assessing disease severity, facilitate the selection of appropriate treatment options, which is important for reducing the spread of the virus, saving lives, and controlling the pandemic.
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spelling pubmed-74735682020-09-14 Chest computed tomography (CT) findings and semiquantitative scoring of 60 patients with coronavirus disease 2019 (COVID-19): A retrospective imaging analysis combining anatomy and pathology Zhang, Hao Jiang, Xu-jing Liu, Xiao-hua Ma, Hong Zhang, Ya-hong Rao, Yue Li, Lin Xu, Hai-yan Lyu, Fa-jin PLoS One Research Article In this study, we ascertained the chest CT data of 60 patients admitted to 3 hospitals in Chongqing with confirmed COVID-19. We conducted anatomical and pathological analyses to elucidate the possible reasons for the distribution, morphology, and characteristics of COVID-19 in chest CT. We also shared a semiquantitative scoring of affected lung segments, which was recommended by our local medical association. This scoring system was applied to quantify the severity of the disease. The most frequent imaging findings of COVID-19 were subpleural ground glass opacities and consolidation; there was a significant difference in semiquantitative scores between the early, progressive, and severe stages of the disease. We conclude that the chest CT findings of COVID-19 showed certain characteristics because of the anatomical features of the human body and pathological changes caused by the virus. Therefore, chest CT is a valuable tool for facilitating the diagnosis of COVID-19 and semiquantitative scoring of affected lung segments may further elucidate diagnosis and assessment of disease severity. This will assist healthcare workers in diagnosing COVID-19 and assessing disease severity, facilitate the selection of appropriate treatment options, which is important for reducing the spread of the virus, saving lives, and controlling the pandemic. Public Library of Science 2020-09-04 /pmc/articles/PMC7473568/ /pubmed/32886711 http://dx.doi.org/10.1371/journal.pone.0238760 Text en © 2020 Zhang et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Zhang, Hao
Jiang, Xu-jing
Liu, Xiao-hua
Ma, Hong
Zhang, Ya-hong
Rao, Yue
Li, Lin
Xu, Hai-yan
Lyu, Fa-jin
Chest computed tomography (CT) findings and semiquantitative scoring of 60 patients with coronavirus disease 2019 (COVID-19): A retrospective imaging analysis combining anatomy and pathology
title Chest computed tomography (CT) findings and semiquantitative scoring of 60 patients with coronavirus disease 2019 (COVID-19): A retrospective imaging analysis combining anatomy and pathology
title_full Chest computed tomography (CT) findings and semiquantitative scoring of 60 patients with coronavirus disease 2019 (COVID-19): A retrospective imaging analysis combining anatomy and pathology
title_fullStr Chest computed tomography (CT) findings and semiquantitative scoring of 60 patients with coronavirus disease 2019 (COVID-19): A retrospective imaging analysis combining anatomy and pathology
title_full_unstemmed Chest computed tomography (CT) findings and semiquantitative scoring of 60 patients with coronavirus disease 2019 (COVID-19): A retrospective imaging analysis combining anatomy and pathology
title_short Chest computed tomography (CT) findings and semiquantitative scoring of 60 patients with coronavirus disease 2019 (COVID-19): A retrospective imaging analysis combining anatomy and pathology
title_sort chest computed tomography (ct) findings and semiquantitative scoring of 60 patients with coronavirus disease 2019 (covid-19): a retrospective imaging analysis combining anatomy and pathology
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7473568/
https://www.ncbi.nlm.nih.gov/pubmed/32886711
http://dx.doi.org/10.1371/journal.pone.0238760
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