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Profiling of immune related genes silenced in EBV-positive gastric carcinoma identified novel restriction factors of human gammaherpesviruses

EBV-associated gastric cancer (EBVaGC) is characterized by high frequency of DNA methylation. In this study, we investigated how epigenetic alteration of host genome contributes to pathogenesis of EBVaGC through the analysis of transcriptomic and epigenomic datasets from NIH TCGA (The Cancer Genome...

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Detalles Bibliográficos
Autores principales:	Fiches, Guillaume N., Zhou, Dawei, Kong, Weili, Biswas, Ayan, Ahmed, Elshafa H., Baiocchi, Robert A., Zhu, Jian, Santoso, Netty
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7473590/ https://www.ncbi.nlm.nih.gov/pubmed/32841292 http://dx.doi.org/10.1371/journal.ppat.1008778

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