Unexpected and Deadly: Three Cases of Bone Marrow Necrosis

Bone marrow necrosis (BMN) is a rare pathological diagnosis, with an incidence of 0.3% to 2%. It is most often associated with hematological malignancies and less commonly due to solid tumors, infections, medications, sickle cell disease, chemotherapy, radiotherapy, or idiopathic causes. We reviewed...

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Detalles Bibliográficos
Autores principales: Chan, Abigail S, Marvania, Nirali V, Burley, Nicholas B, Martinez, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Internal Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7473607/
https://www.ncbi.nlm.nih.gov/pubmed/32905546
http://dx.doi.org/10.7759/cureus.9565
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author Chan, Abigail S
Marvania, Nirali V
Burley, Nicholas B
Martinez, Roberto
author_facet Chan, Abigail S
Marvania, Nirali V
Burley, Nicholas B
Martinez, Roberto
author_sort Chan, Abigail S
collection PubMed
description Bone marrow necrosis (BMN) is a rare pathological diagnosis, with an incidence of 0.3% to 2%. It is most often associated with hematological malignancies and less commonly due to solid tumors, infections, medications, sickle cell disease, chemotherapy, radiotherapy, or idiopathic causes. We reviewed bone marrow biopsies performed in our institution from 2009 to 2019 and found three cases of BMN. Two cases were secondary to neoplastic causes, while the third one was possibly from alcohol abuse.
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spelling pubmed-74736072020-09-04 Unexpected and Deadly: Three Cases of Bone Marrow Necrosis Chan, Abigail S Marvania, Nirali V Burley, Nicholas B Martinez, Roberto Cureus Internal Medicine Bone marrow necrosis (BMN) is a rare pathological diagnosis, with an incidence of 0.3% to 2%. It is most often associated with hematological malignancies and less commonly due to solid tumors, infections, medications, sickle cell disease, chemotherapy, radiotherapy, or idiopathic causes. We reviewed bone marrow biopsies performed in our institution from 2009 to 2019 and found three cases of BMN. Two cases were secondary to neoplastic causes, while the third one was possibly from alcohol abuse. Cureus 2020-08-05 /pmc/articles/PMC7473607/ /pubmed/32905546 http://dx.doi.org/10.7759/cureus.9565 Text en Copyright © 2020, Chan et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Chan, Abigail S
Marvania, Nirali V
Burley, Nicholas B
Martinez, Roberto
Unexpected and Deadly: Three Cases of Bone Marrow Necrosis
title Unexpected and Deadly: Three Cases of Bone Marrow Necrosis
title_full Unexpected and Deadly: Three Cases of Bone Marrow Necrosis
title_fullStr Unexpected and Deadly: Three Cases of Bone Marrow Necrosis
title_full_unstemmed Unexpected and Deadly: Three Cases of Bone Marrow Necrosis
title_short Unexpected and Deadly: Three Cases of Bone Marrow Necrosis
title_sort unexpected and deadly: three cases of bone marrow necrosis
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7473607/
https://www.ncbi.nlm.nih.gov/pubmed/32905546
http://dx.doi.org/10.7759/cureus.9565
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