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Methylation pattern of urinary DNA as a marker of kidney function decline in diabetes
INTRODUCTION: Renal tubular injury contributes to the decline in kidney function in patients with diabetes. Cell type-specific DNA methylation patterns have been used to calculate proportions of particular cell types. In this study, we developed a method to detect renal tubular injury in patients wi...
Autores principales: | Marumo, Takeshi, Hoshino, Junichi, Kawarazaki, Wakako, Nishimoto, Mitsuhiro, Ayuzawa, Nobuhiro, Hirohama, Daigoro, Yamanouchi, Masayuki, Ubara, Yoshifumi, Okaneya, Toshikazu, Fujii, Takeshi, Yuki, Kazunari, Atsumi, Yoshihito, Sato, Atsuhisa, Arai, Eri, Kanai, Yae, Shimosawa, Tatsuo, Fujita, Toshiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7473659/ https://www.ncbi.nlm.nih.gov/pubmed/32883689 http://dx.doi.org/10.1136/bmjdrc-2020-001501 |
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