Bioinspired liquid gating membrane-based catheter with anticoagulation and positionally drug release properties

Catheters are indispensable medical devices that are extensively used in daily medical treatment. However, existing catheter materials continue to encounter many problems, such as thrombosis, single functionality, and inadaptability to environmental changes. Inspired by blood vessels, we develop a s...

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Autores principales: Wang, Chunyan, Wang, Shuli, Pan, Hong, Min, Lingli, Zheng, Huili, Zhu, Huang, Liu, Gang, Yang, Weizhong, Chen, Xinyu, Hou, Xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7473668/
https://www.ncbi.nlm.nih.gov/pubmed/32917618
http://dx.doi.org/10.1126/sciadv.abb4700
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author Wang, Chunyan
Wang, Shuli
Pan, Hong
Min, Lingli
Zheng, Huili
Zhu, Huang
Liu, Gang
Yang, Weizhong
Chen, Xinyu
Hou, Xu
author_facet Wang, Chunyan
Wang, Shuli
Pan, Hong
Min, Lingli
Zheng, Huili
Zhu, Huang
Liu, Gang
Yang, Weizhong
Chen, Xinyu
Hou, Xu
author_sort Wang, Chunyan
collection PubMed
description Catheters are indispensable medical devices that are extensively used in daily medical treatment. However, existing catheter materials continue to encounter many problems, such as thrombosis, single functionality, and inadaptability to environmental changes. Inspired by blood vessels, we develop a self-adaptive liquid gating membrane-based catheter with anticoagulation and positionally drug release properties. Our multifunctional liquid gating membrane-based catheter significantly attenuates blood clot formation and can be used as a general catheter design strategy to offer various drugs positionally releasing applications to comprehensively enhance the safety, functionality, and performance of medical catheters’ materials.
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spelling pubmed-74736682020-09-17 Bioinspired liquid gating membrane-based catheter with anticoagulation and positionally drug release properties Wang, Chunyan Wang, Shuli Pan, Hong Min, Lingli Zheng, Huili Zhu, Huang Liu, Gang Yang, Weizhong Chen, Xinyu Hou, Xu Sci Adv Research Articles Catheters are indispensable medical devices that are extensively used in daily medical treatment. However, existing catheter materials continue to encounter many problems, such as thrombosis, single functionality, and inadaptability to environmental changes. Inspired by blood vessels, we develop a self-adaptive liquid gating membrane-based catheter with anticoagulation and positionally drug release properties. Our multifunctional liquid gating membrane-based catheter significantly attenuates blood clot formation and can be used as a general catheter design strategy to offer various drugs positionally releasing applications to comprehensively enhance the safety, functionality, and performance of medical catheters’ materials. American Association for the Advancement of Science 2020-09-04 /pmc/articles/PMC7473668/ /pubmed/32917618 http://dx.doi.org/10.1126/sciadv.abb4700 Text en Copyright © 2020 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC). https://creativecommons.org/licenses/by-nc/4.0/ https://creativecommons.org/licenses/by-nc/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial license (https://creativecommons.org/licenses/by-nc/4.0/) , which permits use, distribution, and reproduction in any medium, so long as the resultant use is not for commercial advantage and provided the original work is properly cited.
spellingShingle Research Articles
Wang, Chunyan
Wang, Shuli
Pan, Hong
Min, Lingli
Zheng, Huili
Zhu, Huang
Liu, Gang
Yang, Weizhong
Chen, Xinyu
Hou, Xu
Bioinspired liquid gating membrane-based catheter with anticoagulation and positionally drug release properties
title Bioinspired liquid gating membrane-based catheter with anticoagulation and positionally drug release properties
title_full Bioinspired liquid gating membrane-based catheter with anticoagulation and positionally drug release properties
title_fullStr Bioinspired liquid gating membrane-based catheter with anticoagulation and positionally drug release properties
title_full_unstemmed Bioinspired liquid gating membrane-based catheter with anticoagulation and positionally drug release properties
title_short Bioinspired liquid gating membrane-based catheter with anticoagulation and positionally drug release properties
title_sort bioinspired liquid gating membrane-based catheter with anticoagulation and positionally drug release properties
topic Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7473668/
https://www.ncbi.nlm.nih.gov/pubmed/32917618
http://dx.doi.org/10.1126/sciadv.abb4700
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