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Pro4 prolyl peptide bond isomerization in human galectin-7 modulates the monomer-dimer equilibrum to affect function

Human galectin-7 (Gal-7; also termed p53-induced gene 1 product) is a multifunctional effector by productive pairing with distinct glycoconjugates and protein counter-receptors in the cytoplasm and nucleus, as well as on the cell surface. Its structural analysis by NMR spectroscopy detected doubling...

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Detalles Bibliográficos
Autores principales: Miller, Michelle C., Nesmelova, Irina V., Daragan, Vladimir A., Ippel, Hans, Michalak, Malwina, Dregni, Aurelio, Kaltner, Herbert, Kopitz, Jürgen, Gabius, Hans-Joachim, Mayo, Kevin H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7473712/
https://www.ncbi.nlm.nih.gov/pubmed/32766716
http://dx.doi.org/10.1042/BCJ20200499

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