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Inhibition of DNA-PK by gefitinib causes synergism between gefitinib and cisplatin in NSCLC
Lung cancer has the highest incidence and mortality rates among the malignant tumor types world-wide. Platinum-based chemotherapy is the main treatment for advanced non-small-cell lung cancer (NSCLC), and epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) have greatly improved t...
Autores principales: | Pan, Chi, Duan, Huijie, Wu, Yinan, Zhu, Chunpeng, Yi, Chenghao, Duan, Yin, Lu, Demin, Guo, Cheng, Wu, Deqi, Wang, Yanyan, Fu, Xianhua, Xu, Jing, Chen, Yiding, Luo, Meng, Tian, Wei, Pan, Tao, Xu, Wenhong, Zhang, Suzhan, Huang, Jianjin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7473755/ https://www.ncbi.nlm.nih.gov/pubmed/32945394 http://dx.doi.org/10.3892/ijo.2020.5103 |
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