Cdk5-mediated Drp1 phosphorylation drives mitochondrial defects and neuronal apoptosis in radiation-induced optic neuropathy

Radiation-induced optic neuropathy (RION) is a devastating complication following external beam radiation therapy (EBRT) that leads to acute vision loss. To date, no efficient, available treatment for this complication, due partly to the lack of understanding regarding the developmental processes be...

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Detalles Bibliográficos
Autores principales: Rong, Rong, Xia, Xiaobo, Peng, Haiqin, Li, Haibo, You, Mengling, Liang, Zhuotao, Yao, Fei, Yao, Xueyan, Xiong, Kun, Huang, Jufang, Zhou, Rongrong, Ji, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7473761/
https://www.ncbi.nlm.nih.gov/pubmed/32883957
http://dx.doi.org/10.1038/s41419-020-02922-y

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