Cargando…
Reactive oxygen species oxidize STING and suppress interferon production
Reactive oxygen species (ROS) are by-products of cellular respiration that can promote oxidative stress and damage cellular proteins and lipids. One canonical role of ROS is to defend the cell against invading bacterial and viral pathogens. Curiously, some viruses, including herpesviruses, thrive de...
Autores principales: | Tao, Lili, Lemoff, Andrew, Wang, Guoxun, Zarek, Christina, Lowe, Alexandria, Yan, Nan, Reese, Tiffany A |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7473769/ https://www.ncbi.nlm.nih.gov/pubmed/32886065 http://dx.doi.org/10.7554/eLife.57837 |
Ejemplares similares
-
Virus infection is controlled by hematopoietic and stromal cell sensing of murine cytomegalovirus through STING
por: Piersma, Sytse J, et al.
Publicado: (2020) -
The oxygen sensor prolyl hydroxylase domain 2 regulates the in vivo suppressive capacity of regulatory T cells
por: Ajouaou, Yousra, et al.
Publicado: (2022) -
Mitochondrial respiration contributes to the interferon gamma response in antigen-presenting cells
por: Kiritsy, Michael C, et al.
Publicado: (2021) -
The aryl hydrocarbon receptor and interferon gamma generate antiviral states via transcriptional repression
por: Kueck, Tonya, et al.
Publicado: (2018) -
The interferon-inducible GTPase MxB promotes capsid disassembly and genome release of herpesviruses
por: Serrero, Manutea C, et al.
Publicado: (2022)