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A tale of two cell-fates: role of the Hippo signaling pathway and transcription factors in early lineage formation in mouse preimplantation embryos

In mammals, the first cell-fate decision occurs during preimplantation embryo development when the inner cell mass (ICM) and trophectoderm (TE) lineages are established. The ICM develops into the embryo proper, while the TE lineage forms the placenta. The underlying molecular mechanisms that govern...

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Detalles Bibliográficos
Autores principales: Karasek, Challis, Ashry, Mohamed, Driscoll, Chad S, Knott, Jason G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7473788/
https://www.ncbi.nlm.nih.gov/pubmed/32647873
http://dx.doi.org/10.1093/molehr/gaaa052