Pan-cancer study detects genetic risk variants and shared genetic basis in two large cohorts

Deciphering the shared genetic basis of distinct cancers has the potential to elucidate carcinogenic mechanisms and inform broadly applicable risk assessment efforts. Here, we undertake genome-wide association studies (GWAS) and comprehensive evaluations of heritability and pleiotropy across 18 canc...

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Detalles Bibliográficos
Autores principales: Rashkin, Sara R., Graff, Rebecca E., Kachuri, Linda, Thai, Khanh K., Alexeeff, Stacey E., Blatchins, Maruta A., Cavazos, Taylor B., Corley, Douglas A., Emami, Nima C., Hoffman, Joshua D., Jorgenson, Eric, Kushi, Lawrence H., Meyers, Travis J., Van Den Eeden, Stephen K., Ziv, Elad, Habel, Laurel A., Hoffmann, Thomas J., Sakoda, Lori C., Witte, John S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7473862/
https://www.ncbi.nlm.nih.gov/pubmed/32887889
http://dx.doi.org/10.1038/s41467-020-18246-6

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