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Artificial iris performance for smart contact lens vision correction applications

This paper presents the simulated performance assessment of an artificial iris embedded on a scleral contact lens using real data from an aniridia patient. The artificial iris is based on guest–host liquid crystal cells (GH-LCD) in order to actively modify the transmittance of the lens and effective...

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Autores principales: Vásquez Quintero, Andrés, Pérez-Merino, Pablo, De Smet, Herbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7474060/
https://www.ncbi.nlm.nih.gov/pubmed/32887927
http://dx.doi.org/10.1038/s41598-020-71376-1
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author Vásquez Quintero, Andrés
Pérez-Merino, Pablo
De Smet, Herbert
author_facet Vásquez Quintero, Andrés
Pérez-Merino, Pablo
De Smet, Herbert
author_sort Vásquez Quintero, Andrés
collection PubMed
description This paper presents the simulated performance assessment of an artificial iris embedded on a scleral contact lens using real data from an aniridia patient. The artificial iris is based on guest–host liquid crystal cells (GH-LCD) in order to actively modify the transmittance of the lens and effective pupil size. Experimental validation of the GH-LCD spectrum and iris contrast (determined to be 1:2.1) enabled the development of optical models that include the effect of a small pupil on image quality and visual quality on an optical system with aniridia characteristics. Visual simulations at different light conditions (high/low photopic and mesopic) demonstrated the theoretical capacity of the customized artificial iris smart contact lens to expand the depth-of-focus and decrease the optical aberrations (in particular, the spherical aberration). The visual modelling suggests a maximum depth-of-focus value for a 2-mm pupil diameter for both eyes as follows: 3D (1,000 cd/m(2)), 2D (10 cd/m(2)) and 0.75D (1 cd/m(2)). This work demonstrates the beneficial optical effects of an active artificial iris, based on visual simulations in response to different light levels, and enables further experimental investigation on patients to validate the dynamic light attenuation and visual performance of smart contact lenses with GH-LCD.
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spelling pubmed-74740602020-09-08 Artificial iris performance for smart contact lens vision correction applications Vásquez Quintero, Andrés Pérez-Merino, Pablo De Smet, Herbert Sci Rep Article This paper presents the simulated performance assessment of an artificial iris embedded on a scleral contact lens using real data from an aniridia patient. The artificial iris is based on guest–host liquid crystal cells (GH-LCD) in order to actively modify the transmittance of the lens and effective pupil size. Experimental validation of the GH-LCD spectrum and iris contrast (determined to be 1:2.1) enabled the development of optical models that include the effect of a small pupil on image quality and visual quality on an optical system with aniridia characteristics. Visual simulations at different light conditions (high/low photopic and mesopic) demonstrated the theoretical capacity of the customized artificial iris smart contact lens to expand the depth-of-focus and decrease the optical aberrations (in particular, the spherical aberration). The visual modelling suggests a maximum depth-of-focus value for a 2-mm pupil diameter for both eyes as follows: 3D (1,000 cd/m(2)), 2D (10 cd/m(2)) and 0.75D (1 cd/m(2)). This work demonstrates the beneficial optical effects of an active artificial iris, based on visual simulations in response to different light levels, and enables further experimental investigation on patients to validate the dynamic light attenuation and visual performance of smart contact lenses with GH-LCD. Nature Publishing Group UK 2020-09-04 /pmc/articles/PMC7474060/ /pubmed/32887927 http://dx.doi.org/10.1038/s41598-020-71376-1 Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Vásquez Quintero, Andrés
Pérez-Merino, Pablo
De Smet, Herbert
Artificial iris performance for smart contact lens vision correction applications
title Artificial iris performance for smart contact lens vision correction applications
title_full Artificial iris performance for smart contact lens vision correction applications
title_fullStr Artificial iris performance for smart contact lens vision correction applications
title_full_unstemmed Artificial iris performance for smart contact lens vision correction applications
title_short Artificial iris performance for smart contact lens vision correction applications
title_sort artificial iris performance for smart contact lens vision correction applications
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7474060/
https://www.ncbi.nlm.nih.gov/pubmed/32887927
http://dx.doi.org/10.1038/s41598-020-71376-1
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