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Plant-derived secondary metabolites as the main source of efflux pump inhibitors and methods for identification

The upsurge of multiple drug resistance (MDR) bacteria substantially diminishes the effectiveness of antibiotic arsenal and therefore intensifies the rate of therapeutic failure. The major factor in MDR is efflux pump-mediated resistance. A unique pump can make bacteria withstand a wide range of str...

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Detalles Bibliográficos
Autores principales: Seukep, Armel Jackson, Kuete, Victor, Nahar, Lutfun, Sarker, Satyajit D., Guo, Mingquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7474127/
https://www.ncbi.nlm.nih.gov/pubmed/32923005
http://dx.doi.org/10.1016/j.jpha.2019.11.002