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Sarsasapogenin Suppresses RANKL-Induced Osteoclastogenesis in vitro and Prevents Lipopolysaccharide-Induced Bone Loss in vivo

INTRODUCTION: Osteoclasts are giant polynuclear cells; their main function is bone resorption. An increased number of osteoclasts and enhanced bone resorption exert significant effects on osteoclast-related bone-lytic diseases, including osteoporosis. Given the limitations of current therapies for o...

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Detalles Bibliográficos
Autores principales: Peng, Jiaxuan, Zhao, Kangxian, Zhu, Jiling, Wang, Yanben, Sun, Peng, Yang, Qichang, Zhang, Tan, Han, Weiqi, Hu, Wenjun, Yang, Wanlei, Ruan, Jianwei, Qian, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7474134/
https://www.ncbi.nlm.nih.gov/pubmed/32943842
http://dx.doi.org/10.2147/DDDT.S256867