Cargando…

Quantifying Fibrinogen-Dependent Aggregation of Red Blood Cells in Type 2 Diabetes Mellitus

Fibrinogen is regarded as the main glycoprotein in the aggregation of red blood cells (RBCs), a normally occurring phenomenon that has a major impact on blood rheology and hemodynamics, especially under pathological conditions, including type 2 diabetes mellitus (T2DM). In this study, we investigate...

Descripción completa

Detalles Bibliográficos
Autores principales:	Deng, Yixiang, Papageorgiou, Dimitrios P., Li, Xuejin, Perakakis, Nikolaos, Mantzoros, Christos S., Dao, Ming, Karniadakis, George Em
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Biophysical Society 2020
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7474208/ https://www.ncbi.nlm.nih.gov/pubmed/32814061 http://dx.doi.org/10.1016/j.bpj.2020.07.026

Ejemplares similares

Deep transfer learning and data augmentation improve glucose levels prediction in type 2 diabetes patients
por: Deng, Yixiang, et al.
Publicado: (2021)

A deep convolutional neural network for classification of red blood cells in sickle cell anemia
por: Xu, Mengjia, et al.
Publicado: (2017)

MD/DPD Multiscale Framework for Predicting Morphology and Stresses of Red Blood Cells in Health and Disease
por: Chang, Hung-Yu, et al.
Publicado: (2016)

The role of omics in the pathophysiology, diagnosis and treatment of non-alcoholic fatty liver disease
por: Perakakis, Nikolaos, et al.
Publicado: (2020)

Association of Adipokines with Development and Progression of Nonalcoholic Fatty Liver Disease
por: Boutari, Chrysoula, et al.
Publicado: (2018)

Patient-specific modeling of individual sickle cell behavior under transient hypoxia
por: Li, Xuejin, et al.
Publicado: (2017)

PCSK9 inhibition and cholesterol homeostasis in insulin producing β-cells
por: Päth, Günter, et al.
Publicado: (2022)

Multiphysics and multiscale modeling of microthrombosis in COVID-19
por: Li, He, et al.
Publicado: (2022)

Short-term treatment with high dose liraglutide improves lipid and lipoprotein profile and changes hormonal mediators of lipid metabolism in obese patients with no overt type 2 diabetes mellitus: a randomized, placebo-controlled, cross-over, double-blind clinical trial
por: Peradze, Natia, et al.
Publicado: (2019)

Mechanics of diseased red blood cells in human spleen and consequences for hereditary blood disorders
por: Li, He, et al.
Publicado: (2018)

Both Elafibranor and Liraglutide Improve NAFLD / NASH but Affect Differentially the Hepatic Lipidome and Metabolome in a Diet-Induced Obese and Biopsy-Confirmed Mouse Model of NASH
por: Perakakis, Nikolaos, et al.
Publicado: (2021)

Empagliflozin Improves Metabolic and Hepatic Outcomes in a Non-Diabetic Obese Biopsy-Proven Mouse Model of Advanced NASH
por: Perakakis, Nikolaos, et al.
Publicado: (2021)

A combined computational and experimental investigation of the filtration function of splenic macrophages in sickle cell disease
por: Li, Guansheng, et al.
Publicado: (2023)

Simultaneous polymerization and adhesion under hypoxia in sickle cell disease
por: Papageorgiou, Dimitrios P., et al.
Publicado: (2018)

Inflow/Outflow Boundary Conditions for Particle-Based Blood Flow Simulations: Application to Arterial Bifurcations and Trees
por: Lykov, Kirill, et al.
Publicado: (2015)

Quantitative prediction of erythrocyte sickling for the development of advanced sickle cell therapies
por: Lu, Lu, et al.
Publicado: (2019)

Leptin alters energy intake and fat mass but not energy expenditure in lean subjects
por: Chrysafi, Pavlina, et al.
Publicado: (2020)

Blood Viscosity in Subjects With Type 2 Diabetes Mellitus: Roles of Hyperglycemia and Elevated Plasma Fibrinogen
por: Sun, Jiehui, et al.
Publicado: (2022)

How the spleen reshapes and retains young and old red blood cells: A computational investigation
por: Li, He, et al.
Publicado: (2021)

Analyses of internal structures and defects in materials using physics-informed neural networks
por: Zhang, Enrui, et al.
Publicado: (2022)

A General Shear-Dependent Model for Thrombus Formation
por: Yazdani, Alireza, et al.
Publicado: (2017)

AOSLO-net: A Deep Learning-Based Method for Automatic Segmentation of Retinal Microaneurysms From Adaptive Optics Scanning Laser Ophthalmoscopy Images
por: Zhang, Qian, et al.
Publicado: (2022)

Synergistic Integration of Laboratory and Numerical Approaches in Studies of the Biomechanics of Diseased Red Blood Cells
por: Li, He, et al.
Publicado: (2018)

Numerical methods for stochastic partial differential equations with white noise
por: Zhang, Zhongqiang, et al.
Publicado: (2017)

Variable-Order Fractional Models for Wall-Bounded Turbulent Flows
por: Song, Fangying, et al.
Publicado: (2021)

The Selective Peroxisome Proliferator‐Activated Receptor Gamma Modulator CHS‐131 Improves Liver Histopathology and Metabolism in a Mouse Model of Obesity and Nonalcoholic Steatohepatitis
por: Perakakis, Nikolaos, et al.
Publicado: (2020)

Extraction of mechanical properties of materials through deep learning from instrumented indentation
por: Lu, Lu, et al.
Publicado: (2020)

Artificial intelligence velocimetry and microaneurysm-on-a-chip for three-dimensional analysis of blood flow in physiology and disease
por: Cai, Shengze, et al.
Publicado: (2021)

Fibrinogen Gamma Chain Promotes Aggregation of Vesicular Stomatitis Virus in Saliva
por: Anschau, Valesca, et al.
Publicado: (2020)

Multiscale Modeling of Red Blood Cell Mechanics and Blood Flow in Malaria
por: Fedosov, Dmitry A., et al.
Publicado: (2011)

Systems biology informed deep learning for inferring parameters and hidden dynamics
por: Yazdani, Alireza, et al.
Publicado: (2020)

Computational investigation of blood cell transport in retinal microaneurysms
por: Li, He, et al.
Publicado: (2022)

G2Φnet: Relating genotype and biomechanical phenotype of tissues with deep learning
por: Zhang, Enrui, et al.
Publicado: (2022)

Physics-informed neural networks for predicting gas flow dynamics and unknown parameters in diesel engines
por: Nath, Kamaljyoti, et al.
Publicado: (2023)

Fibrinogen Glycation and Presence of Glucose Impair Fibrin Polymerization—An In Vitro Study of Isolated Fibrinogen and Plasma from Patients with Diabetes Mellitus
por: Luzak, Boguslawa, et al.
Publicado: (2020)

Fibrinogen, Fibrinogen-like 1 and Fibrinogen-like 2 Proteins, and Their Effects
por: Sulimai, Nurul H., et al.
Publicado: (2022)

Hypochlorite-induced aggregation of fibrinogen underlies a novel antioxidant role in blood plasma
por: Mañucat-Tan, Noralyn, et al.
Publicado: (2020)

Role of Fibrinogen in Type-2 Diabetes Mellitus with Diabetic Neuropathy and its Preliminary Mechanism
por: Gu, Wei-Li, et al.
Publicado: (2023)

The plasma protein fibrinogen stabilizes clusters of red blood cells in microcapillary flows
por: Brust, M., et al.
Publicado: (2014)

Commentary: COVID-19 and diabetes mellitus: What we know, how our patients should be treated now, and what should happen next
por: Angelidi, Angeliki M., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_ove3uk7nj4fkcaun7j9kbr9qmr