Cargando…

EGCG Attenuates Renal Damage via Reversing Klotho Hypermethylation in Diabetic db/db Mice and HK-2 Cells

To explore whether epigallocatechin-3-gallate (EGCG) improves renal damage in diabetic db/db mice and high-glucose- (HG-) induced injury in HK-2 cells by regulating the level of Klotho gene promoter methylation. Western blotting was used to detect the protein expression levels of DNA methyltransfera...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Xiu Hong, Zhang, Bao Long, Zhang, Xiao Meng, Tong, Jin Dong, Gu, Yan Hong, Guo, Li Li, Jin, Hui Min
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7474393/ https://www.ncbi.nlm.nih.gov/pubmed/32908633 http://dx.doi.org/10.1155/2020/6092715

Ejemplares similares

Epigallocatechin-3-gallate Attenuates Renal Damage by Suppressing Oxidative Stress in Diabetic db/db Mice
por: Yang, Xiu Hong, et al.
Publicado: (2016)

EGCG-derived polymeric oxidation products enhance insulin sensitivity in db/db mice
por: Wu, Ximing, et al.
Publicado: (2022)

Clopidogrel delays and can reverse diabetic nephropathy pathogenesis in type 2 diabetic db/db mice
por: Li, Hong-Qin, et al.
Publicado: (2022)

Pyruvate-Enriched Oral Rehydration Solution Improves Glucometabolic Disorders in the Kidneys of Diabetic db/db Mice
por: Zhang, Xiao Meng, et al.
Publicado: (2020)

Increased Oxidative Damage of RNA in Early-Stage Nephropathy in db/db Mice
por: Wang, Wan-Xia, et al.
Publicado: (2017)

Erythropoietin Reduces Insulin Resistance via Regulation of Its Receptor-Mediated Signaling Pathways in db/db Mice Skeletal Muscle
por: Pan, Yu, et al.
Publicado: (2017)

Astaxanthin Attenuates the Apoptosis of Retinal Ganglion Cells in db/db Mice by Inhibition of Oxidative Stress
por: Dong, Ling-Yan, et al.
Publicado: (2013)

Reversibility of β-Cell-Specific Transcript Factors Expression by Long-Term Caloric Restriction in db/db Mouse
por: Sheng, Chunjun, et al.
Publicado: (2016)

Losartan reverses permissive epigenetic changes in renal glomeruli of diabetic db/db mice
por: Reddy, Marpadga A., et al.
Publicado: (2013)

CERA Attenuates Kidney Fibrogenesis in the db/db Mouse by Influencing the Renal Myofibroblast Generation
por: Fischer, Christin, et al.
Publicado: (2018)

Liraglutide attenuates hepatic iron levels and ferroptosis in db/db mice
por: Song, Ji-Xian, et al.
Publicado: (2022)

Anti-diabetic activities of catalpol in db/db mice
por: Bao, Qinwen, et al.
Publicado: (2016)

Shengmai San Ameliorates Myocardial Dysfunction and Fibrosis in Diabetic db/db Mice
por: Zhao, Juan, et al.
Publicado: (2016)

Klotho Depletion Contributes to Increased Inflammation in Kidney of the db/db Mouse Model of Diabetes via RelA (Serine)(536) Phosphorylation
por: Zhao, Yanhua, et al.
Publicado: (2011)

Red clover extract exerts antidiabetic and hypolipidemic effects in db/db mice
por: QIU, LONGXIN, et al.
Publicado: (2012)

Celastrol, an NF-κB Inhibitor, Improves Insulin Resistance and Attenuates Renal Injury in db/db Mice
por: Kim, Jung Eun, et al.
Publicado: (2013)

Duodenal-Jejunal Bypass Surgery Reverses Diabetic Phenotype and Reduces Obesity in db/db Mice
por: Liang, Yongjun, et al.
Publicado: (2017)

Dioscin Reduces Vascular Damage in the Retina of db/db Mice by Inhibiting the VEGFA Signaling Pathway
por: Wang, Jun, et al.
Publicado: (2022)

Tangshen Formula Attenuates Diabetic Nephropathy by Promoting ABCA1-Mediated Renal Cholesterol Efflux in db/db Mice
por: Liu, Peng, et al.
Publicado: (2018)

S-Propargyl-Cysteine Attenuates Diabetic Cardiomyopathy in db/db Mice Through Activation of Cardiac Insulin Receptor Signaling
por: Li, Ye, et al.
Publicado: (2021)

Olmesartan Medoxomil, An Angiotensin II-Receptor Blocker, Ameliorates Renal Injury In db/db Mice
por: Zhu, Ye, et al.
Publicado: (2019)

Astragaloside IV ameliorates renal injury in db/db mice
por: Sun, Huili, et al.
Publicado: (2016)

Resistin Production from Adipose Tissue Is Decreased in db/db Obese Mice, and Is Reversed by Rosiglitazone
por: Ye, Hongying, et al.
Publicado: (2013)

Rhein reversal of DNA hypermethylation-associated Klotho suppression ameliorates renal fibrosis in mice
por: Zhang, Qin, et al.
Publicado: (2016)

Deletion of Smad3 protects against diabetic myocardiopathy in db/db mice
por: Dong, Li, et al.
Publicado: (2021)

Growth hormone-releasing hormone agonist attenuates vascular calcification in diabetic db/db mice
por: Ren, Hao-Lin, et al.
Publicado: (2023)

Glycyrrhizic Acid Prevents Diabetic Nephropathy by Activating AMPK/SIRT1/PGC-1α Signaling in db/db Mice
por: Hou, Shaozhang, et al.
Publicado: (2017)

Protective Role of Tangshen Formula on the Progression of Renal Damage in db/db Mice by TRPC6/Talin1 Pathway in Podocytes
por: Wang, Qian, et al.
Publicado: (2020)

Dapagliflozin protects against nonalcoholic steatohepatitis in db/db mice
por: Qiao, Panshuang, et al.
Publicado: (2022)

EW-7197 Attenuates the Progression of Diabetic Nephropathy in db/db Mice through Suppression of Fibrogenesis and Inflammation
por: Ha, Kyung Bong, et al.
Publicado: (2022)

Eicosapentaenoic and docosahexaenoic acids attenuate hyperglycemia through the microbiome-gut-organs axis in db/db mice
por: Zhuang, Pan, et al.
Publicado: (2021)

Jinlida Granules Reduce Obesity in db/db Mice by Activating Beige Adipocytes
por: Zhou, Hong-ru, et al.
Publicado: (2022)

Cosmos DB for MongoDB developers: migrating to Azure Cosmos DB and using the MongoDB API
por: Sharma, Manish
Publicado: (2018)

Stevia and Stevioside Attenuate Liver Steatosis through PPARα-Mediated Lipophagy in db/db Mice Hepatocytes
por: Park, Miey, et al.
Publicado: (2022)

Tangshen formula attenuates hepatic steatosis by inhibiting hepatic lipogenesis and augmenting fatty acid oxidation in db/db mice
por: Kong, Qin, et al.
Publicado: (2016)

Liver X receptor agonist treatment attenuates cardiac dysfunction in type 2 diabetic db/db mice
por: He, Qing, et al.
Publicado: (2014)

Fecal Transplantation from db/db Mice Treated with Sodium Butyrate Attenuates Ischemic Stroke Injury
por: Wang, Huidi, et al.
Publicado: (2021)

Comparative Proteomic Analysis of Liver Tissues and Serum in db/db Mice
por: Zhang, Yu, et al.
Publicado: (2022)

Berberine-loaded solid lipid nanoparticles are concentrated in the liver and ameliorate hepatosteatosis in db/db mice
por: Xue, Mei, et al.
Publicado: (2015)

Hepatic overexpression of protein targeting to glycogen attenuates obesity and improves hyperglycemia in db/db mice
por: López-Soldado, Iliana, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_ecq288hm1bj749e651cvol607l