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Patientenantikörper als Informationsquelle

Since decades antibodies are used for diagnosis e. g. by detecting patient antibodies that specifically bind to Influenza virus proteins. We predict these diagnostic questions will be parallelized to diagnose all known disease specific antibodies at once. These tests will ask in addition, which unkn...

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Detalles Bibliográficos
Autores principales: Falk, Fabian, Zhou, Zekun, Klinkusch, Andreas, Weber, Laura, Breitling, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7474495/
https://www.ncbi.nlm.nih.gov/pubmed/32921927
http://dx.doi.org/10.1007/s12268-020-1440-0
Descripción
Sumario:Since decades antibodies are used for diagnosis e. g. by detecting patient antibodies that specifically bind to Influenza virus proteins. We predict these diagnostic questions will be parallelized to diagnose all known disease specific antibodies at once. These tests will ask in addition, which unknown antibodies patrol in a patient’s blood, and what exactly they bind to. Thereby, we expect to find antibody species that correlate to hitherto enigmatic diseases or have specialized functions.