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A new generation of vaccines based on alphavirus self-amplifying RNA

DNA or mRNA vaccines have potential advantages over conventional vaccines since they are easier to manufacture and have higher safety profiles. In particular, self-amplifying RNA (saRNA) derived from alphavirus expression vectors has shown to be very efficient to induce humoral and cellular response...

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Detalles Bibliográficos
Autores principales: Ballesteros-Briones, María Cristina, Silva-Pilipich, Noelia, Herrador-Cañete, Guillermo, Vanrell, Lucia, Smerdou, Cristian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7474593/
https://www.ncbi.nlm.nih.gov/pubmed/32898764
http://dx.doi.org/10.1016/j.coviro.2020.08.003