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Agonist-induced formation of unproductive receptor-G(12) complexes
G proteins are activated when they associate with G protein-coupled receptors (GPCRs), often in response to agonist-mediated receptor activation. It is generally thought that agonist-induced receptor-G protein association necessarily promotes G protein activation and, conversely, that activated GPCR...
Autores principales: | Okashah, Najeah, Wright, Shane C., Kawakami, Kouki, Mathiasen, Signe, Zhou, Joris, Lu, Sumin, Javitch, Jonathan A., Inoue, Asuka, Bouvier, Michel, Lambert, Nevin A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7474645/ https://www.ncbi.nlm.nih.gov/pubmed/32817560 http://dx.doi.org/10.1073/pnas.2003787117 |
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