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Single-molecule diffusometry reveals no catalysis-induced diffusion enhancement of alkaline phosphatase as proposed by FCS experiments

Theoretical and experimental observations that catalysis enhances the diffusion of enzymes have generated exciting implications about nanoscale energy flow, molecular chemotaxis, and self-powered nanomachines. However, contradictory claims on the origin, magnitude, and consequence of this phenomenon...

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Detalles Bibliográficos
Autores principales:	Chen, Zhijie, Shaw, Alan, Wilson, Hugh, Woringer, Maxime, Darzacq, Xavier, Marqusee, Susan, Wang, Quan, Bustamante, Carlos
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2020
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7474647/ https://www.ncbi.nlm.nih.gov/pubmed/32817484 http://dx.doi.org/10.1073/pnas.2006900117

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